Close

We use cookies to improve your experience of our website. Privacy Policy

Skip to main content

Materials Research Institute

Search
Menu

Dr Isabel Palacios

Isabel Palacios

Lecturer in Cell Biology

School of Biological and Chemical Sciences
Room 3.13, Fogg Building
+44 (0)20 7882 6909

www.qmul.ac.uk/sbcs/staff/isabelpalacios.html

Research

cell and tissue biophysics, cytoskeletal forces and proteins during germline development

Research Interests

Dr Isabel Palacios is a lecturer on the Nanchang Joint Programme at Queen Mary University of London and a visitor scientist at the University of Cambridge. She has extensive research experience and has worked in various research positions at the University of Cambridge for over 12 years. Dr Palacios completed her PhD studies at the European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. She has been successful in obtaining various grants from distinguished institutions such as the BBSRC, the Wellcome Trust, CRUK and Alzheimer’s Research UK. 

Publications of specific relevance to Materials Research

Publications

2020

  • Santa-Cruz Mateos C, Valencia-Expósito A, Palacios IM and Martín-Bermudo MD (2020). Integrins regulate epithelial cell shape by controlling the architecture and mechanical properties of basal actomyosin networks. Public Library of Science (Plos)  Plos Genetics  vol. 16, (6) e1008717-e1008717. 10.1371/journal.pgen.1008717
  • Drechsler M, Lang LF, Al-Khatib L, Dirks H, Burger M, Schönlieb C-B and Palacios IM (2020). Optical flow analysis reveals that Kinesin-mediated advection impacts on the orientation of microtubules in the Drosophila oocyte. American Society For Cell Biology  Molecular Biology of The Cell  mbcE1908044-mbcE1908044. 10.1091/mbc.E19-08-0440

2019

  • Francis D, Chanana B, Fernandez B, Gordon B, Mak T and Palacios IM (2019). YAP/Yorkie in the germline modulates the age-related decline of germline stem cells and niche cells. Plos One  vol. 14, (4) 10.1371/journal.pone.0213327

2017

  • PALACIOS IM (2017). Active diffusion and advection in Drosophila oocytes result from the interplay of actin and microtubules. Nature Publishing Group  Nature Communications  vol. 8, 10.1038/s41467-017-01414-6
  • Martín-Bermudo MD, Gebel L and Palacios IM (2017). DrosAfrica: Building an African biomedical research community using Drosophila. Elsevier Bv  Seminars in Cell & Developmental Biology  vol. 70, 58-64. 10.1016/j.semcdb.2017.08.044

2016

  • Ng BF, Selvaraj GK, Santa-Cruz Mateos C, Grosheva I, Alvarez-Garcia I, Martín-Bermudo MD and Palacios IM (2016). α-Spectrin and integrins act together to regulate actomyosin and columnarization, and to maintain a monolayered follicular epithelium. Journal of Cell Science  vol. 129, (9) e1.2-e1.2. 10.1242/jcs.191288
  • Ng BF, Selvaraj GK, Santa-Cruz Mateos C, Grosheva I, Alvarez-Garcia I, Martín-Bermudo MD and Palacios IM (2016). α-Spectrin and integrins act together to regulate actomyosin and columnarization, and to maintain a monolayered follicular epithelium. The Company of Biologists  Development  vol. 143, (8) 1388-1399. 10.1242/dev.130070
  • Saavedra P, Brittle A, Palacios IM, Strutt D, JoséCasal and Lawrence PA (2016). Planar cell polarity: The Dachsous/Fat system contributes differently to the embryonic and larval stages of Drosophila. Biology Open  vol. 5, (4) 397-408. 10.1242/bio.017152

2014

  • Saavedra P, Vincent JP, Palacios IM, Lawrence PA and Casal J (2014). Plasticity of both planar cell polarity and cell identity during the development of Drosophila. Elife  vol. 2014, (3) 10.7554/eLife.01569
  • Palacios IM (2014). Hop-on hop-off: Polysomes take a tour of the cell on endosomes. Journal of Cell Biology  vol. 204, (3) 287-289. 10.1083/jcb.201401019
  • Williams LS, Ganguly S, Loiseau P, Ng BF and Palacios IM (2014). The auto-inhibitory domain and ATP-independent microtubulebinding region of Kinesin heavy chain are major functional domains for transport in the Drosophila germline. Development (Cambridge)  vol. 141, (1) 176-186. 10.1242/dev.097592
  • Jesús Gómez-Lamarca M, Cobreros-Reguera L, Ibáñez-Jiménez B, Palacios IM and Martín-Bermudo MD (2014). Integrins regulate epithelial cell differentiation by modulating Notch activity. Journal of Cell Science  vol. 127, (21) 4667-4678. 10.1242/jcs.153122

2013

  • Palacios IM (2013). Nonsense-mediated mRNA decay: From mechanistic insights to impacts on human health. Briefings in Functional Genomics  vol. 12, (1) 25-36. 10.1093/bfgp/els051
  • Roca-Varela ML and Palacios IM (2013). How are spoken skills assessed in proficiency tests of general English as a Foreign Language? A preliminary survey. International Journal of English Studies  vol. 13, (2) 53-68. 10.6018/ijes.13.2.185901

2012

  • Ganguly S, Williams LS, Palacios IM and Goldstein RE (2012). Cytoplasmic streaming in Drosophila oocytes varies with kinesin activity and correlates with the microtubule cytoskeleton architecture. Proceedings of The National Academy of Sciences of The United States of America  vol. 109, (38) 15109-15114. 10.1073/pnas.1203575109

2011

  • Avery P, Vicente-Crespo M, Francis D, Nashchekina O, Alonso CR and Palacios IM (2011). Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner. Rna  vol. 17, (4) 624-638. 10.1261/rna.2404211
  • Vicente-Crespo M and Palacios IM (2011). Nonsense-mediated mRNA decay and development: Shoot the messenger to survive? (Biochemical Society Transactions (2010) 38, (1500-1505)). Biochemical Society Transactions  vol. 39, (1) 10.1042/bst0390411v

2010

  • Vicente-Crespo M and Palacios IM (2010). Nonsense-mediated mRNA decay and development: Shoot the messenger to survive? Biochemical Society Transactions  vol. 38, (6) 1500-1505. 10.1042/BST0381500
  • Loiseau P, Davies T, Williams LS, Mishima M and Palacios IM (2010). Drosophila PAT1 is required for Kinesin-1 to transport cargo and to maximize its motility. Development  vol. 137, (16) 2763-2772. 10.1242/dev.048108

2007

  • Meignin C, Alvarez-Garcia I, Davis I and Palacios IM (2007). The Salvador-Warts-Hippo Pathway Is Required for Epithelial Proliferation and Axis Specification in Drosophila. Current Biology  vol. 17, (21) 1871-1878. 10.1016/j.cub.2007.09.062
  • Palacios IM (2007). How does an mRNA find its way? Intracellular localisation of transcripts. Seminars in Cell and Developmental Biology  vol. 18, (2) 163-170. 10.1016/j.semcdb.2007.01.008

2004

  • Palacios IM, Gatfield D, St. Johnston D and Izaurralde E (2004). An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay. Nature  vol. 427, (6976) 753-757. 10.1038/nature02351

2003

  • Macchi P, Kroening S, Palacios IM, Baldassa S, Grunewald B, Ambrosino C, Goetze B, Lupas A, St. Johnston D and Kiebler M (2003). Barentsz, a new component of the Staufen-containing ribonucleoprotein particles in mammalian cells, interacts with Staufen in an RNA-dependent manner. Journal of Neuroscience  vol. 23, (13) 5778-5788. 10.1523/jneurosci.23-13-05778.2003

2002

  • Palacios IM and St Johnston D (2002). Kinesin light chain-independent function of the Kinesin heavy chain in cytoplasmic streaming and posterior localisation in the Drosophila oocyte. Development  vol. 129, (23) 5473-5485. 10.1242/dev.00119
  • Benton R, Palacios IM and Johnston DS (2002). Drosophila 14-3-3/PAR-5 is an essential mediator of PAR-1 function in axis formation. Developmental Cell  vol. 3, (5) 659-671. 10.1016/S1534-5807(02)00320-9
  • Palacios IM (2002). RNA processing: Splicing and the cytoplasmic localisation of mRNA. Current Biology  vol. 12, (2) 10.1016/S0960-9822(01)00671-6

2001

  • Palacios IM and Johnston DST (2001). Getting the message across: The intracellular localization of mRNAs in higher eukaryotes. Annual Review of Cell and Developmental Biology  vol. 17, 569-614. 10.1146/annurev.cellbio.17.1.569
  • Van Eeden FJM, Palacios IM, Petronczki M, Weston MJD and St. Johnston DS (2001). Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole. Journal of Cell Biology  vol. 154, (3) 511-523. 10.1083/jcb.200105056